Disease-prevention efforts organized by the late former president drove cases of the torturous parasitic illness, Guinea worm disease, down from 3.6 million to 13.

President Jimmy Carter spent four years in the Oval Office, but his legacy extends far beyond the White House. The former head of state died on Sunday, December 29, in his home in Plains, Ga., aged 100, after nearly two years in hospice care. In the decades since he left public office, Carter delivered a significant contribution to public health in the world’s poorest nations.